Ibogaine the same as Ayahuasca? Short answer? No. Both are sacred plant medicines, but their experiences and mechanisms are very different.
— Ibogaine creates a oneiric, dreamlike state, often described as a deep internal life review.
— Ayahuasca can feel more like traveling through other dimensions.
Neurologically:
— Ibogaine helps reset dopamine and serotonin systems, increases GDNF (a key neurotrophic factor), and promotes long-term neuroplasticity. It can interrupt addiction, reduce cravings, and support cognitive enhancement, PTSD recovery, and emotional clarity with lasting effects.
— Ayahuasca is more commonly associated with ego dissolution.
With ibogaine, you’re clear, grounded, and deeply introspective. Both can be powerful healing tools, but ibogaine uniquely targets the brain and nervous system to help break long-standing patterns at their root.